High Quality for Taste Masking Excipients - n-methylbenzamide|CAS 613-93-4|C8H9NO|Guanlang – Guanlang

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High Quality for Taste Masking Excipients - n-methylbenzamide|CAS 613-93-4|C8H9NO|Guanlang – Guanlang Detail:

We are one of the leading n-methylbenzamide suppliers and manufacturers in china, if you want to find n-methylbenzamide factory, feel free to contact us and drop us a email.

1. What’s N-Methylbenzamide?

N-methylbenzamide is an effective phosphodiesterase 10A (pde10a) inhibitor. N-methylbenzamide has anticancer activity.PDE10A is a recently identified phosphodiesterase with a quite remarkable localization since the protein is abundant only in brain tissue. Based on this unique localization, research has focused extensively on using PDE10A modulators as a novel therapeutic approach for dysfunction in the basal ganglia circuit including Parkinson’s disease, Huntington’s disease, schizophrenia, addiction and obsessive compulsive disorder. Medicinal chemistry efforts identified the N-methyl-N-[4-(quinolin-2-ylmethoxy)-phenyl]-isonicotinamide as a nanomolar PDE10A inhibitor. A subsequent Lead-optimization program identified analogous N-methylanilides and their corresponding N-methylbenzamide as potent PDE10A inhibitors, concurrently some interesting and unexpected binding modes were identified.

Melting point 76-78 ° C

Boiling point 167 ° C

Density 1.1031

Refractive index 1.5589

Storage conditions sealed dry, room temperature

Solubility ethanol: soluble 50mg / ml,water solubility:Insoluble in Water

CAS: 613-93-4

Appearance: White Crystalline

2. Main application

Inhibitor, anticancer,organic synthesis intermediate,laboratories chemicals

3.Storage and Packing

3.First aid measures

Eye Contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention.

Skin Contact: Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes.

Inhalation: Remove from exposure, lie down. Remove to fresh air. If not breathing, give artificial respiration.

Ingestion: Clean mouth with water. Get medical attention.

Most important symptoms and effects: No information available.

Self-Protection of the First Aider: No special precautions required.

Notes to Physician: Treat symptomatically.

4. Transport information

Road and Rail Transport : Not Regulated

IMDG/IMO : Not regulated

IATA : Not regulated

Special Precautions for User: No special precautions required

5. HTML5 spectrum

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Our company insists all along the quality policy of "product good quality is base of enterprise survival; buyer fulfillment will be the staring point and ending of an company; persistent improvement is eternal pursuit of staff" and also the consistent purpose of "reputation very first, shopper first" for High Quality for Taste Masking Excipients - n-methylbenzamide|CAS 613-93-4|C8H9NO|Guanlang – Guanlang, The product will supply to all over the world, such as: Algeria, Monaco, Mecca, Good quality and reasonable price have brought us stable customers and high reputation. Providing 'Quality Products, Excellent Service, Competitive Prices and Prompt Delivery', we are now looking forward to even greater cooperation with overseas customers based on mutual benefits. We'll work whole-heartedly to improve our solutions and services. We also promise to work jointly with business partners to elevate our cooperation to a higher level and share success together. Warmly welcome you to visit our factory sincerely.

Hebei Guanlang Biotechnology Co., Ltd. belongs to Guanlang Group, which was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector among Beijing Tianjin and Hebei and has advantage of convenient transportation . Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.We have our own factory and lab,also offer customized synthesis service for our customers.

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