Factory wholesale Intermediate Pharma - n-methylbenzamide|CAS 613-93-4|C8H9NO|Guanlang – Guanlang Detail:
We are one of the leading n-methylbenzamide suppliers and manufacturers in china, if you want to find n-methylbenzamide factory, feel free to contact us and drop us a email.
1. What’s N-Methylbenzamide?
N-methylbenzamide is an effective phosphodiesterase 10A (pde10a) inhibitor. N-methylbenzamide has anticancer activity.PDE10A is a recently identified phosphodiesterase with a quite remarkable localization since the protein is abundant only in brain tissue. Based on this unique localization, research has focused extensively on using PDE10A modulators as a novel therapeutic approach for dysfunction in the basal ganglia circuit including Parkinson’s disease, Huntington’s disease, schizophrenia, addiction and obsessive compulsive disorder. Medicinal chemistry efforts identified the N-methyl-N-[4-(quinolin-2-ylmethoxy)-phenyl]-isonicotinamide as a nanomolar PDE10A inhibitor. A subsequent Lead-optimization program identified analogous N-methylanilides and their corresponding N-methylbenzamide as potent PDE10A inhibitors, concurrently some interesting and unexpected binding modes were identified.
Melting point 76-78 ° C
Boiling point 167 ° C
Density 1.1031
Refractive index 1.5589
Storage conditions sealed dry, room temperature
Solubility ethanol: soluble 50mg / ml,water solubility:Insoluble in Water
CAS: 613-93-4
Appearance: White Crystalline
2. Main application
Inhibitor, anticancer,organic synthesis intermediate,laboratories chemicals
3.Storage and Packing
3.First aid measures
Eye Contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention.
Skin Contact: Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes.
Inhalation: Remove from exposure, lie down. Remove to fresh air. If not breathing, give artificial respiration.
Ingestion: Clean mouth with water. Get medical attention.
Most important symptoms and effects: No information available.
Self-Protection of the First Aider: No special precautions required.
Notes to Physician: Treat symptomatically.
4. Transport information
Road and Rail Transport : Not Regulated
IMDG/IMO : Not regulated
IATA : Not regulated
Special Precautions for User: No special precautions required
5. HTML5 spectrum
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Cooperation
We always get the job done to be a tangible staff to ensure that we can easily offer you the best high-quality and the greatest value for Factory wholesale Intermediate Pharma - n-methylbenzamide|CAS 613-93-4|C8H9NO|Guanlang – Guanlang, The product will supply to all over the world, such as: The Swiss, Sacramento, Irish, We expect to provide products and services to more users in global aftermarket markets; we launched our global branding strategy by providing our excellent products all over the world by virtue of our well reputed partners letting global users keep pace with technology innovation and achievements with us.
Hebei Guanlang Biotechnology Co., Ltd. belongs to Guanlang Group, which was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector among Beijing Tianjin and Hebei and has advantage of convenient transportation . Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.We have our own factory and lab,also offer customized synthesis service for our customers.
By Klemen Hrovat from Australia - 2017.08.18 18:38
A good manufacturers, we have cooperated twice, good quality and good service attitude.
By Zoe from Poland - 2017.07.28 15:46
