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Amphotericin B is an antifungal medication used for serious fungal infections and leishmaniasis.The fungal infections it is used to treat include aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, and cryptococcosis. For certain infections it is given with flucytosine. It is typically given by injection into a vein.
Synonyms: ABELCET;Halizon;LNS-AmB;AMBISOME;Abelecet;fungilin;Amphocin;AMPHOZONE;FUNGIZONE
Common side effects include a reaction with fever, chills, and headaches soon after the medication is given, as well as kidney problems. Allergic symptoms including anaphylaxismay occur. Other serious side effects include low blood potassium and inflammation of the heart.It appears to be relatively safe in pregnancy. There is a lipid formulation that has a lower risk of side effects.It is in the polyene class of medications and works in part by interfering with the cell membrane of the fungus.
Amphotericin B (Fungilin, Fungizone, Abelcet, AmBisome, Fungisome, Amphocil, Amphotec) is a polyene antifungal , often used intravenously for systemic fungal infections.
Amphotericin B was originally extracted from Streptomyces nodosus, a filamentousbacterium.
Application of Amphotericin B
systemic fungal infections.
Amphotericin B is the only effective treatment for some fungal infections.
Function of Amphotericin B1. Antifungal
One of the main intravenous uses for Amphotericin B is in treating various systemic fungal infections (e.g.,
in critically ill, comorbidly infected or immunocompromised patients), including cryptococcal meningitis.Amphotericin B is also commonly used in tissue culture to prevent fungi from contaminating cell cultures.
Amphotericin B is usually sold in a concentrated solution, either on its own or in combination with the
antibiotics penicillin and streptomycin.
Hebei Guanlang Biotechnology Co., Ltd. belongs to Guanlang Group, which was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector among Beijing Tianjin and Hebei and has advantage of convenient transportation . Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.We have our own factory and lab,also offer customized synthesis service for our customers.